Posted on

Pizza guy who delivered to Academy Awards collects $1,000 tip

Pizza guy who delivered to Academy Awards collects $1,000 tip

http://twitter.com/#!/wheatus/status/440597344342773760

Yeah, what about that pizza guy who delivered those pies to the Academy Awards ceremony Sunday night? TMZ reported that he’d left the building a much more famous man but without the tip money the celebs had collected in Pharrell Williams’ hat.

The pizza guy did appear on Ellen DeGeneres’ show today, though, and DeGeneres was extra generous by adding to the $600 hat tip to make it a cool even grand.

http://twitter.com/#!/GenuineGent_x/status/440606221469380608
http://twitter.com/#!/CarissaKnapp1/status/440637244236255232
http://twitter.com/#!/DonnaBertrand/status/440636766475677696

Read more: http://twitchy.com/2014/03/03/pizza-guy-who-delivered-to-academy-awards-collects-1000-tip/

Posted on

17 Times Quinn Morgendorffer Was The Smartest Person On “Daria”

17 Times Quinn Morgendorffer Was The Smartest Person On "Daria"

1. When she encouraged Daria to never give up:

Viacom

2. When she wrote a heartbreaking work of staggering truth:

Viacom

Viacom

Viacom

 

3. When she gave important relationship advice:

4. When defending her fashion choices:

5. When she knew exactly how you felt about school:

Viacom

6. When she maintained her high standards:

Viacom

7. When she was fair and just:

Viacom

8. When she was a trailblazer for women everywhere:

Viacom

9. When she acted fast in an emergency:

Viacom

Viacom

Viacom

 

10. When having to make an important decision:

Viacom

Viacom

 

11. When she defended the importance of physical beauty:

Viacom

12. When she was a prodigy at geometry:

Viacom

13. When she just exercised good common sense:

Viacom / Via okaydaria.tumblr.com

14. When she kept Sandi’s perspective in check:

Viacom

Viacom

 

15. When she never forgot the horror of yesterday:

Viacom

16. When she stood up for the rights of her people:

Viacom

17. When she inspired others to reach their potential:

Viacom

Viacom

 

Read more: http://buzzfeed.com/kristinchirico/times-quinn-morgendorffer-was-the-smartest-person-on-dari

Posted on

Why You Should Worry About The Privatization Of Genetic Data

Why You Should Worry About The Privatization Of Genetic Data

The Conversation

President Obama has promised to support a bold future for medicine where diagnostic testing and treatments arent just whats best for most people theyre whats best for you.

This precision medicine takes individual variations in our genes and environments into account. Getting there will require genetic and health data from as many people as possible to uncover the relationship between genetic differences and medical outcomes.

This is why Obamas Precision Medicine Initiative (PMI) includes the creation of a million-person research cohort. Participants will provide blood and urine samples, share information from their electronic health records and answer questions about health and lifestyle. The hope is that this trove of data will reveal the genetic underpinnings for a variety of diseases, leading to personalized diagnostics and treatments.

Its a bold goal, and one that private companies have a head start on. For instance, 23andMe, a direct-to-consumer genetic testing company, already has a 1.2 million person genetic database.

But genetic data banks amassed by private companies dont necessarily have to follow the same regulations regarding access to their data that federally funded researchers do. And a recent proposal to change consent regulations for human research may make it cheaper for private companies to collect and use this data than public ones.

As bioethicists (myself included) have warned, we need to pay attention to concerns about how these private genetic data banks are used and accessed before we enable a system where the future of public genetic research lies in private hands.

Who can access genetic data?

If you go to a clinic or a hospital to have your blood drawn for a diagnostic test or tissue removed, many will keep that biospecimen, and put it or the data derived from it into a bio- or data bank for future research.

As long as future research with your specimen or associated data doesnt include any information that links it back to you (like your name), researchers dont need your consent to do their work (though this may change).

If researchers receive federal funding, they often have to submit their data to a public data bank such as the National Institutes of Healths dbGaP, which charges other researchers little to nothing to access this data for future work. Open accessibility is also the goal for the PMI Cohort.

In contrast, private companies like 23andMe, the breast cancer testing company Myriad or the carrier-screening company Counsyl generally get their biospecimens and health data from paying customers who buy genetic tests from them.

Some of these private companies are sharing data with other researchers. For instance, 23andMe collaborated with researchers at Pfizer and Massachusetts General Hospital on the largest-ever study about the genetic causes of major depression. The company also collaborated with Stanford School of Medicine on a study about skin cancer. Both studies were made possible by data from the companys consumers (the financial details of these arrangements are unclear).

Also recently, Counsyl, collaborating with a researcher at Columbia University Medical Center, published a large study on expanded carrier screening (the genetic test it sells).

Its great that these research collaborations are happening, but collaboration isnt the same thing as open access. Private companies are still the ultimate gatekeeper for their data. They choose whom they share their data with. And researchers generally dont have the same level of access to private data banks that they do from existing public data banks or (hopefully) the future PMI Cohort.

When research is done using genetic data that arent accessible, it is harder for other researchers to check scientific claims a concern most recently brought up in an editorial accompanying the research based on Counsyls private data bank.

Some companies can sell genetic data

23andMe can keep and sell its customers’ genetic information to others because consumers consent to the sale of their anonymous and aggregate information just by purchasing the product and agreeing to its privacy statement. The company can also sell deidentified individual-level data if you sign the research consent document which 80 percent of consumers do.

These data are valuable: 23andMe recently announced that the drug company Genetech offered to pay up to US$60 million to use its database to conduct Parkinsons research.

And the fact 23andMe can sell data puts a worrying spin on the proposed changes to consent for federally funded human research.

At the moment, federally funded researchers and private companies have the same standards for consent: If human biospecimens are not identifiable, they dont have to ask for consent to use them for research.

However, the government recently proposed revisions to the federal human subjects research regulations that would require federally funded researchers to get what is called broad consent from people to use their biospecimens (it is unclear what effect this would have on private/public collaborations at the moment). This would apply even if researchers wont know who the specimens came from. Broad consent would include a general description of types of research that might be conducted with the biospecimen.

While many reasonably argue that this is the right thing to do, it will be expensive. One medical school recently estimated that it would cost them an additional $4 million a year to spend the predicted extra 10 minutes per participant to get informed consent and track who said what. But there are other potential unintended consequences.

For example, these new requirements wont necessarily apply to private companies. This difference in consent standards could encourage a system (as I recently argued) where private companies bring in biospecimens and data, deidentify them, and sell them back to publicly funded researchers for less than it would cost for the researchers to collect samples and donor consent themselves.

The future of genetic research

If the future of medicine is being launched from biospecimens and related data, we need to think through their storage and access thoughtfully. Its all too easy to create monopolies, which can have dire implications for equitable access.

Take Myriad Genetics. It provides the best diagnostic testing for uncommon genetic variants associated with breast and ovarian cancer (BRCA1 and BRCA2). Myriad held a patent on these genes for over a decade, until 2013, preventing anyone else from doing this type of testing. Even though its patents were invalidated, Myriad still has the biggest BRCA database on the market and remains the leader in the field.

The advantage of Myriads monopoly is cyclical: The patents allowed it to accumulate the best data, the best data allow it to offer the best results and the best results mean people keep contributing their data. In this cycle, genetic data with incredible health research potential become just another business asset.

Private industry partnerships can and should play a critical and helpful role in the future of medical research. But our medical information is more than a business asset for private leverage. We need to make sure that public genetics researchers are private industrys partners, not dependents, and that we enable public banks so private ones do not become monopolies.

The future of precision medicine must come from pieces and data from us all and we need to ensure a data banking system that will be able to benefit us all in return.

The ConversationKayte Spector-Bagdady, Postdoctoral Research Fellow, Center for Bioethics & Social Sciences in Medicine, University of Michigan

This article was originally published on The Conversation. Read the original article.

Read more: http://www.iflscience.com/health-and-medicine/why-you-should-worry-about-the-privatization-of-genetic-data/

Posted on

Moms’ Tips for Baby Sleep (Video)

Phillips Avent viral videoPhillips Avent viral video

Moms show their best tips for making cranky, crying babies fall asleep in the new Phillips Avent viral ad.

Thanks Vincenzo!

Posted on

Community Post: The Night Before Your First Final: Expectation Vs. Reality

Community Post: The Night Before Your First Final: Expectation Vs. Reality

1. Expectation: You’ve been reading and studying dutifully for the past 2 weeks. This exam can suck it.

2. Reality: Exam? What exam?

Shit. That was this Wednesday?

3. Expectation: At this point, you’ve got studying down to a science.

4. Reality: Turns out, studying just isn’t that much fun.

BBC Films / Via petite-cerise.tumblr.com

5. Expectation: You’ve got the perfect pump-up playlist for exam day.

Focus Features / Via fabfunny.com

6. Reality: You didn’t remember a playlist so you’re stuck with top 40 or talk radio.

7. Expectation: You make sure you get your 8+ hours of sleep before the big day.

8. Reality: The only way you’re going to make a reasonable attempt at this is with all-nighters (plural.)

Walt Disney Pictures / Via xtakemetoneverlandx.tumblr.com

9. Expectation: You’ve worked hard. You’ve studied as hard as you could.

10. Reality: You didn’t really work all that hard. In fact, you didn’t really study at all.

11. Expectation: You know there’s a point where you can’t fit any more information into your brain.

Nickelodeon / Via adventuretime.wikia.com

12. Reality: That point just came a bit sooner than you thought it would…

Fox

13. Expectation: Where you’ll be at 11:00pm.

Walt Disney Television / Via mygifdump.tumblr.com

14. Reality: Where you’ll be at 11:00pm.

20th Century Fox / Via rebloggy.com

15. Expectation: Come the next morning, you rise early in time for a proper breakfast.

Walt Disney Television / Via gifake.net

16. Reality: You oversleep and only have time for one thing.

Warner Bros. Television / Via friday-night-dinner.tumblr.com

17. Expectation: Exam, do your worst!

18. Reality: WAIT NO PLEASE DON’T.

Fox

19. But come tomorrow, it will all be over.

20. Until the next one….

22. So from one of the wisest people we know:

23. And one of the not so wise:

Walt Disney Pictures

24. GOOD LUCK ON YOUR FINALS!!!

Lionsgate / Via quickmeme.com

Read more: http://buzzfeed.com/autumnrc/the-night-before-your-first-final-expectation-vs-gr0c

Posted on

10 Lessons In Love I Learned From Losing The Love Of My Life At 19

10 Lessons In Love I Learned From Losing The Love Of My Life At 19

Maison ScotchMaison Scotch

Maison Scotch

Six years have passed — it took two years to finally be able to see a future for myself again and four years to come to a point of acceptance.

The vision of a fairytale life diminished in my 19-year-old eyes, when my high school sweetheart was diagnosed with cancer. He died within the month.

Gone were three years of building dreams and a promising future filled with love and adventure. Gone was any hope.

Six years have passed — it took two years to finally be able to see a future for myself again and four years to come to a point of acceptance.

All I know is it was a privilege to have been part of his life, for he taught me everything I now know about what it means to love another human being and how it feels to be loved in return.

Here are the lessons I have learned on the journey, in loving memory of a boy who truly lived:

1. Say I love you

If you feel a particular way at any moment, acknowledge it. Share it with the people you love. If you feel grateful, say, “Thank you,” and if you feel love, say, “I love you.”

Though people believe when you say it so often, the words lose their meaning, I’ll never get to say it to him again.

What are we all waiting for? Just say it! There is no such thing as the “right time.” The right time could pass you by.


2. Communicate more openly

There were many things left unsaid because it was scary to open up and talk about feelings, especially those involving death. I knew he was terrified of dying, but I wish we spoke about it more.

Talking to people and sharing my thoughts and emotions definitely helped me grieve. It releases a lot of pent-up tension and mental anxiety. You don’t have to deal with everything on your own. People are willing to listen.


3. Listen carefully

We should all take the time to listen to one another more often. Sometimes, emotions are screaming to be heard. Lending an ear to someone is one of the best ways to be there.

It’s so easy to slip into our unconscious worlds, especially with the distractions of technology and social media. If you listen enough, you might hear something that could save a person’s life.


4. Respect one another

Respect is something that is cultivated and nurtured over time. You can show someone your respect by valuing his or her opinions and decisions, and treating him or her with fairness and care.

I respected my partner’s decision to not undergo stem cell chemotherapy; he knew his body would not cope with the procedure. He expected me to debate with him and fight for him to try the treatment, but I respected his decision because he knew his body better than I did.

I already watched him endure an immense amount of pain. It was his will, and I did my best to understand.


5. Pay attention to the little things

If you blink, you’ll miss them. There were so many moments I took for granted that came flooding back, long after he was gone. The importance of being present around the ones you love can never be overstated.

It’s the little moments that count. Savor them.


6. Support each other’s dreams

I always go back to the late nights, when we sat outside in his car and talked about the dreams we had for our future. He wanted to be this crazy entrepreneur with his own gym and airline, and I believed he was crazy enough to do it.

He’d encourage me to start teaching in my garage and planned ways we could draw students into my classroom.

He always found ways to make me better, rather than allow me to believe in my insecurities of not being capable or good enough.

It means the world when the people you love most believe in you and want to help you achieve your goals. Your dreams may change over time, but how powerful they felt in that moment will last forever.


7. Take care of your body

We’ve all heard this one: Your body is your temple. We know it, and yet, not all of us treat our bodies with such care.

Even after losing him to cancer, I struggled to love and nurture my body. I put it under a lot of stress and put on a lot of weight. I’ve come to love it a lot more now by making sure I eat well and exercise often. I make it a routine.

My partner was also a fit guy. The pace at which cancer deteriorated his body was frightening, as cancer thrives in younger bodies. But, it reminded me that it’s necessary to stay strong and healthy to live well.


8. Do what you love

It is not worth it to live day-in and day-out doing things that make you sad and tired. That’s just another way to put your health in decline.

My partner was a living testament of the importance in doing what you love. Even in his sick and frail state, he refused to give up his love for sports.

It’s not advisable to push yourself to the limits when you are not well enough to do so, but he made sure he played that last game of footy with the boys while he could.

When you do what you love, it makes your heart sing. It gives you passion and purpose.


9. Dream big

Life is too short, right? We fear dreams that are bigger than us; we fear failure without even trying, and we fear success before even getting there. That’s a lot of fear in which to live.

I miss his fearlessness and his ability to boldly declare something as outrageous as being the next Richard Branson.

He never got the chance to fulfill these dreams, as his life got cut short. Only then did I realize that my days are numbered, too. How do I make them count?


10. Love unconditionally

If you’re going to love, don’t just do it in bits and pieces. Love fully, open your heart up completely and embrace every moment.

Though you run the risk of getting hurt, you’ll never feel the entire beauty of love in its purest form without doing so.

Love as much as you can so you’ll never feel the regret of not having loved enough. Loving him gave me the greatest joy, and being loved by him was the greatest blessing.

Read more: http://elitedaily.com/dating/learned-from-losing-the-love-of-my-life/864473/

Posted on

Big Papi channels his inner Rodney Dangerfield

http://twitter.com/#!/jwelbes/status/204912156758646785

Despite the multi-millions he’s currently making for playing a game, Red Sox slugger David Ortiz is complaining that he gets no respect from fans or Boston’s front office.

“I don’t get no respect,” he said. “Not from the media. Not from the front office. What I do is never the right thing. It’s always hiding, for somebody to find out.”

Wow. We really really feel sorry for Big Papi. It must be hell going to work everyday, swinging a bat at a few balls, getting paid millions and millions of dollars and getting absolutely no respect for it.

Hang in there, Ortiz! Your life will surely get better soon.

David Ortiz. Doesn't care what people think or say about him. But feels need to speak out that he gets no respect. Right.

— Danny Picard (@DannyPicard) May 22, 2012

So, David Ortiz thinks he gets "no respect" from Boston front office? I guess millions of $$$ is an insult, eh?

— dwbudd (@dwbudd) May 22, 2012

Read more: http://twitchy.com/2012/05/22/big-papi-channels-his-inner-rodney-dangerfield/

Posted on

Bindi Irwins Haunting Halloween Tango Scores Yet Another Perfect 10 on Dancing With the Stars!

Bindi Irwins Haunting Halloween Tango Scores Yet Another Perfect 10 on Dancing With the Stars!

She said nobody has seen her tough side, but she really vamped it up for this spine-chilling performance!

Bindi Irwin has been rocking DTWS left and right with perfect-10 performances. Since her emotional tribute to her fatherSteve Irwin last month, the 17-year-old is continuing to captivate the audience and blow the judges awaywith every step. But Bindi says nobody has really seen the tough side of her untillast night.

With each act dedicated to her Dad, she pours her soul out on the dance floor with every move. This week’s theme was Halloween, and though her partner Derek Hough says Bindi couldn’t be scary if she triedthis little vampire proved him all wrong with this fangtastic performance! Once again: Perfect 10!

Read more: http://www.faithit.com/bindi-irwins-haunting-halloween-tango-scores-yet-another-perfect-10-on-dancing-with-the-stars/

Posted on

9-Year-Old Skateboarder Successfully Lands a 540 After 75 Tries

9-Year-Old Skateboarder Successfully Lands a 540 After 75 Tries

Watch out, Tony Hawk. This kid is shredding her way to the top.

At age 9, most young skateboarders are just learning to ollie, happy to successfully jump their boards a few inches.

Sabre Norris from New South Wales, Australia, can’t ride a bike, but has already tackled the halfpipe and landed her first 540. The trick requires the rider launch off a ramp, spin with the board one-and-a-half turns and successfully land back on the ramp.

skatebaord small

Video: YouTube, The Berrics

The video shows a few failed landings, but after 75 attempts that day, Norris finally landed the 540, according to The Berrics.

Her reaction to landing the trick is just as good as the feat itself.